Definition Of Deoxyhemoglobin. Deoxyhemoglobin: The form of hemoglobin without oxygen, the predominant protein in red blood cells. Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygen-loaded form it is oxyhemoglobin and is bright red. In the oxygen-unloaded form it is called deoxyhemoglobin and is purple-blue.
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